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Much better CYP3A4 inhibitors for example ketoconazole or itraconazole could be anticipated to have greater effects than noticed with saquinavir. A beginning dose of twenty five mg of VIAGRA must be thought of in clients having erythromycin or strong CYP3A4 inhibitors (including saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTRATION